The fight against sickle cell disease: how one hospital in rural Maharashtra is making a difference

Dawn Kuruvilla I know sickle cell disease (SCD) less from the medical textbooks and more from the suffering of patients I’ve treated. Over time, this

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Environmental Factor – December 2019: Connecting Parkinson’s disease, pesticides, and genes

Research by Beate Ritz, M.D., Ph.D., from the University of California at Los Angeles, untangles complex interactions between genetic variation, pesticide exposure, and Parkinson’s disease.

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Environmental Factor – January 2020: Chronic inflammation needs focused research to reduce disease

A new paper highlights the toll on life and health from chronic inflammatory diseases, which are at the root of more than half the deaths

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Environmental Factor – April 2020: Link between high-fat diet and liver disease reported

One major goal of Wade’s lab is to understand how environmental exposures alter gene activity via chemical modifications to DNA that do not involve changes

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Environmental Factor – October 2024: Protein plays paradoxical roles in preventing and promoting disease

A powerful protein called NRF2 acts like a commander in the antioxidant response, unleashing an army of detoxifying enzymes to protect against oxidative stress and

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Environmental Factor – July 2020: Canine companions shed light on chemicals and disease

Thirty canine companions participated in the study, wearing silicone tags attached to their collars. This pooch belongs to first author Catherine Wise. (Photo courtesy of

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Environmental Factor – July 2020: Linking exposures to later-life disease — webinars draw hundreds

Suk directs SRP, which fosters interdisciplinary research approaches to address the problems associated with potentially hazardous environmental exposures. (Photo courtesy of Steve McCaw) The challenge

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Environmental Factor – September 2020: Biological signs of disease examined at National Academies event

Exposure to environmental and social stressors can cause molecular changes that lead to poor health outcomes, but identifying which changes are true indicators of adverse

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Environmental Factor – November 2020: Mitochondrial dysfunction, disease explored through prestigious award

Mitochondria generate energy for cells and play important roles in metabolism, immunity, calcium signaling, and other processes, but they must interact with other organelles to

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Environmental Factor – January 2021: Triclosan worsens fatty liver disease in mice

NIEHS-funded researchers at the University of California (UC) San Diego found evidence that triclosan — an antimicrobial found in medical soaps and household products —

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