Environmental Factor – April 2019: Repair protein uses filaments to bridge broken DNA

Williams is head of the Structural Cell Biology Group at the NIEHS, and holds a secondary appointment in the Signal Transduction Laboratory. (Photo courtesy of

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Environmental Factor – May 2019: Barton on DNA electrochemistry at NIEHS Distinguished Lecture

Early in her career, Jacqueline Barton, Ph.D., was among the first to observe that DNA provides a medium for electron transfer, or movement of an

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Environmental Factor – July 2019: Aging and cell stress harm DNA in similar ways

New findings from NIEHS researchers could point to novel strategies for preventing or treating cancer and neurodegenerative diseases. The study, published May 8 in PLoS

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Environmental Factor – August 2019: Cellular traffic cop directs DNA transcription

Jothi holds a secondary appointment in the Biostatistics and Computational Biology Branch. (Photo courtesy of Steve McCaw) A recent study led by NIEHS scientist Raja

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Environmental Factor – September 2019: Molecular sensor scouts DNA damage, supervises repair

In the time it takes you to read this sentence, every cell in your body experiences some form of DNA damage. Without vigilant repair, cancer

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Environmental Factor – July 2020: DNA repair discovery holds promise for precision cancer therapy

Williams’ lab continues to study APE2, working with other NIEHS researchers to further understand the role and regulation of APE2 in processing ribonucleotides embedded in

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Environmental Factor – November 2020: Double-strand DNA breaks repaired by protein called polymerase mu

Bebenek said polymerase mu is remarkable because the enzyme seems to have evolved to deal with unstable targets, such as double-strand DNA breaks. (Photo courtesy

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Environmental Factor – December 2020: DNA Repair special issue honors renowned expert Sam Wilson

Wilson and his collaborators have published hundreds of scientific papers on DNA repair pathways and related topics. (Photo courtesy of Steve McCaw) A special issue

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Environmental Factor – February 2021: Even skin shielded from sun shows DNA changes from UV light

For the first time, scientists have measured the different types of DNA changes that occur across all genes in human skin cells. In a paper

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Environmental Factor – April 2021: Cutting DNA is risky business

The DNA double helix is an iconic structure. But this structure can get bent out of shape as its strands are replicated or transcribed. As

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